4,5-Dihydroxytryptamine (4,5-DHT) is a serotonergic neurotoxin of the tryptamine family. It is structurally related to the monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). The drug is also a monoamine reuptake inhibitor. Its analogue 4-hydroxy-5-methoxytryptamine (4-HO-5-MeO-T) is also a serotonergic neurotoxin. Rapid auto-oxidation of 4,5-DHT and 4-HO-5-MeO-T prevents them from being used as serotonergic neurotoxins in scientific research.
See also
- 5,6-Dihydroxytryptamine (5,6-DHT)
- 5,7-Dihydroxytryptamine (5,7-DHT)
- Psilomethoxin (4-HO-5-MeO-N,N-DMT)
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